from Biotics Research Corporation supplies 2,000 IU per drop of vitamin D3 as a micro-emulsion for enhanced absorption and utilization, which is particularly important for those with malabsorption conditions. Clinical use of Biotics’ micro-emulsified vitamin D provides significant improvements in serum levels of 25-OH-vitamin D following supplementation.

- Conservative regimen of

supplies necessary vitamin D (as emulsified D3) without the increased risk of hypercalcemia commonly associated with single, large dose therapies - especially important in an outpatient setting.

- One (1) drop daily of

(2,000 IU) increased 25(OH)D concentrations in vitamin D deficient children 202% in six weeks, effectively tripling 25(OH)D levels.

- Simply dispense one (1) drop from the bottle directly onto the tongue each day.

contains no artificial colorants or flavorings and no propylene glycol.

- Of the three regimens tested, the one using Bio-D-Mulsion Forte

is by far the most cost effective. (less than a nickel per day - less than $1.50 per month!)

Evidence clearly suggests vitamin D deficiency/insufficiency is widespread in the developed world. Additionally, we now know the previously defined Upper Limit for safe intake of vitamin D was set far too low, and the physiologic requirement is significantly higher than previously believed. With the discovery of vitamin D receptors in tissues other than the gut and bone - particularly the brain, breast, prostate and lymphocytes - recent research suggests the utilization of higher amounts of supplemental vitamin D3 for a wider range of applications in order to maintain and improve patients’ health.

from Biotics Research Corporation supplies vitamin D3 as a micro-emulsion for enhanced absorption and utilization, which is particularly important for those with malabsorption conditions. Clinical use of Biotics’ micro-emulsified vitamin D provides significant improvements in serum levels of 25-OH-vitamin D following supplementation.

While we are all familiar with the importance of vitamin D in calcium absorption and bone metabolism, many may not be aware of the recent research on vitamin D and the widening range of applications available for cholecalciferol, which can be classified as both a vitamin and a pro-hormone.

Additionally, while it has commonly been assumed the upper limit of safe intake is approximately 1,000 IU per day, we now know that the physiologic requirement of vitamin D may be as high as 4,000 IU per day, which is less than half of the 10,000 IU that can be produced endogenously with just a few minutes of sun exposure.

Vitamin D Deficiency and Musculoskeletal Health Vitamin D deficiency is associated with dull, achy musculoskeletal pain that is incompletely responsive to both pharmacologic and manual therapies. The pain may be widespread or confined to a particular area, most commonly the lower back and lumbar spine.

1. Norman AW. Vitamin D. In: Brown ML (Editor). Present Knowledge in Nutrition. Sixth Edition. Washington: International Life Sciences Institute Nutrition Foundation; 1990. P.108-116

2. Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr. 1999 May; 69(5):842-56  Available on-line at http://www.ajcn.org/cgi/reprint/69/5/842.pdf

3. Holick M F. Vitamin D deficiency: what a pain it is. Mayo Clin Proc. 2003 Dec;78(12):1457-9

4. Al Faraj S, Al Mutairi K. Vitamin D deficiency and chronic low back pain in Saudi Arabia. Spine. 2003 Jan 15;28(2):177-9

5. Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc. 2003 Dec;78(12):1463-70

6. Lansdowne AT, Provost SC. Vitamin D3 enhances mood in healthy subjects during winter. Psychopharmacology (Berl). 1998 Feb;135(4):319-23

Indeed, several clinical investigations have recently shown vitamin D deficiency is particularly common among people with musculoskeletal pain.

Both the peripheral and central nervous systems have multiple sites of action for vitamin D, and it appears likely that vitamin D modulates serotonin and melatonin synthesis and metabolism.

Alterations in vitamin D levels appear to explain, at least in part, the adverse psychological effects of sunlight deprivation that often occur due to geographic location and climate.

Preliminary evidence suggests vitamin D deficiency may also be particularly common among patients with inflammatory and autoimmune disorders, and that vitamin D may modulate inflammatory responses.

Biotics Research Corporation’s vitamin D is micro-emulsified to enhance absorption and utilization, which are particularly important for those with malabsorption conditions. Independent clinical experience suggests the micro-emulsion form of vitamin D provides significant improvements in serum levels of 25-OH-vitamin D following supplementation.

With an increased knowledge of the importance of maintaining adequate vitamin D levels, many clinicians recommend supplementation and annual screening for 25-OH-vitamin D levels, especially for patients at risk for deficiency as well as those who may benefit from supplementation.

* These statements have not been evaluated by the
Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.